Re-test your knowledge

Summary

Now that you have completed Module 2 Sleep mechanisms and QUVIVIQ™ action, you should have a better understanding of the wake-sleep mechanisms and hyperarousal, QUVIVIQ™ mode of action and dosing/ administration, and sleep hygiene rules. To test your knowledge, answer the questions below and see how your score has improved.

NICE: National Institute for Health and Care Excellence

QUVIVIQ™ is indicated for the treatment of adult patients with insomnia characterised by symptoms present for at least 3 months and considerable impact on daytime functioning.6

This information is intended for UK healthcare professionals.

This medicine is subject to additional monitoring.

Adverse events must be reported. Healthcare professionals are asked to report any suspected adverse reactions via www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in Google Play or Apple App Store. Adverse events should also be reported to ds.safety.uk@idorsia.com

References

  1. Roch C, Bergamini G et al. Nonclinical pharmacology of daridorexant: a new dual orexin receptor antagonist for the treatment of insomnia. Psychopharmacology 2021;238(10):2693-2708
  2. Saper C B, Scammell T et al. Hypothalamic regulation of sleep and circadian rhythms. Nature 2005;437(7063):1257-1263
  3. Philips A J K, Robinson P A. A quantitative model of sleep-wake dynamic based on the physiology of the brainstem ascending arousal system. J Biol Rhythms 2007;22(2):167-179
  4. Morin C M, Drake C L et al. Insomnia disorder. Nat Rev Dis Primers 2015;1:15026
  5. National Institute for Health and Care Excellence (NICE). Clinical knowledge summary. Insomnia. Scenario: managing short-term insomnia (less than 3 months duration), May 2025. Available at: cks.nice.org.uk. Accessed August 2025
  6. QUVIVIQ™ Idorsia Pharmaceuticals Ltd, Summary of Product Characteristics

© NICE 2023 Daridorexant for treating long-term insomnia. Available from www.nice.org.uk/guidance/ta922. All rights reserved. Subject to Notice of rights.

NICE guidance is prepared for the National Health Service in England. All NICE guidance is subject to regular review and may be updated or withdrawn. NICE accepts no responsibility for the use of its content in this product/ publication.

UK-DA-00654 | Date of preparation: September 2025

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