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Viv is struggling with chronic insomnia

Not an actual patient

Living with the consequences of insomnia for months or years

Has tried many things to improve her sleep:

  • Non-prescription remedies
  • Relaxation techniques
  • Better sleep hygiene
  • Previously trialled prescription medication, though not treated currently

Finding it hard to keep up with her daily responsibilities

Adverse events must be reported. Healthcare professionals are asked to report any suspected adverse reactions via www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in Google play or Apple App store. Adverse events should also be reported to ds.safety.uk@idorsia.com.

This site is intended only for healthcare professionals resident in the United Kingdom.

UK-DA-00123 I Date of preparation: June 2023
Copyright © 2023 Idorsia Pharmaceuticals Ltd

At night, patients with chronic insomnia may be a state of hyperarousal1

In chronic insomnia, research suggests that wake-promoting regions of the brain may be overactive both night and day (hyperarousal).1,2

 

Orexin is a neurotransmitter that promotes wakefulness and provides a specific target for intervention.3

QUVIVIQ™ works differently to sedating hypnotics by blocking the action of orexin, reducing wake-drive and allowing restorative sleep to occur without altering the proportion of sleep stages3‑5

  1. Morin CM, et al. Nat Rev Dis Primers. 2015; 1: 15026.
  2. Nofzinger E, et al. Am J Psychiatry. 2004; 161: 2126–2129.
  3. Roch C, et al. Psychopharmacology. 2021; 238(10): 2693–2708.
  4. QUVIVIQ™ Idorsia Pharmaceuticals LTD, summary of product characteristics.Last updated: March 2023.
  5. Chaput JP, et al. Nat Sci Sleep. 2018; 10: 421–430.
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UK-DA-00445 | Date of preparation: May 2024

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